Processos bioqu\u00edmicos e biof\u00edsicos que ocorrem ao n\u00edvel das membranas das c\u00e9lulas humanas, bem como dos seus agentes patog\u00e9nicos virais e bacterianos. Estudo das duas etapas do ciclo de vida dos v\u00edrus envelopados (principalmente HIV-1 e v\u00edrus da dengue) que envolvem biomembranas – a entrada do v\u00edrus ou do seu conte\u00fado na c\u00e9lula-alvo e a forma\u00e7\u00e3o de novos viri\u00f5es. Estudo da liga\u00e7\u00e3o do fibrinog\u00e9nio \u00e0 membrana eritrocit\u00e1ria e da sua import\u00e2ncia como fator de risco cardiovascular.<\/p>\n\n
Avalia\u00e7\u00e3o pr\u00e9-cl\u00ednica da atividade membranar e do mecanismo de a\u00e7\u00e3o a n\u00edvel molecular dos p\u00e9ptidos antimicrobianos (AMP) e dos p\u00e9ptidos de penetra\u00e7\u00e3o celular (CPP). Na \u00e1rea da Nanotecnologia\/Nanomedicina, estamos tamb\u00e9m a trabalhar no desenvolvimento de sistemas inovadores de biossensores, com maior seletividade e sensibilidade (por exemplo, nanopart\u00edculas e biossensores baseados em amiloide).<\/p>\n","protected":false},"featured_media":0,"template":"","acf":{"header_image":false,"ongoing_projects":"","selected_publications":"","useful_links":"","awards":"","funding":"","sponsorship":"","extra_information":false,"location":"Lisboa","subtitle":"Biomembranas e nanomedicina","team_leader":"","order":"320","is_external":false,"related_research_areas":[1500,1502],"lab_members":[{"ID":8308,"post_author":"1004","post_date":"2025-05-27 13:42:56","post_date_gmt":"2025-05-27 13:42:56","post_content":"","post_title":"Nuno 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