Isabel Gordo Lab

Evolutionary Biology

The area of research of the group led by Isabel Gordo is microbial evolution. The research group combine both theoretical and empirical work with the aim at a better understanding of the major forces that shape variation in bacterial populations.

Present and future projects of the research team include:

• Study the process of adaptation in the context of ecosystems, specifically the mammalian intestine, in health and in disease conditions.
• Test theoretical models of adaptive evolution against genotypic and phenotypic data obtained in experimentally adapted bacterial populations.

Determine the the cost of antibiotic resistance and the level of epistatic interactions on fitness between resistant mutations and the underlying mechanisms causing such epistasis.